The beautiful area of Agoura was first inhabited by the Chumash Indians, friendly Indians who were able to survive here because of the natural springs and streams in the Santa Monica Mountains. They were skilled in farming, hunting and fishing, establishing homes in both coastal and inland locations. The acorn was a major food source, according to Charlie Cook, a fifth generation hereditary chief of the Chumash. Acorns were collected and ground into a mush. It is said in the old days before the Spanish came, the Chumash conducted seasonal burns every 3 to 5 years. This produced better plant life and better food sources, and never hurt the many oak trees.

Later, the Franciscan friars came to the area and set out to educate the Chumash in European ways, hoping to convert them to their way of life and teachings. The California missions were established and connected by the El Camino Real, the main roadway running from Los Angeles to San Francisco which was formerly a Chumash trail. This road ran through the heart of what is now the City of Agoura Hills.